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Control of toxic cyanobacteria bloom with lytic cyanophage and UV

College
College of Public Health
Researchers
Lee, Jiyoung
Jiang, Xuewen
Licensing Manager
Dahlman, Jason "Jay"
614/292-7945
dahlman.3@osu.edu

TS-039477 — Cynophage Ma-LEP and Ultraviolet light can be used in combination as a sustainable and economically friendly method of managing toxic cyanobacteria blooms.

Cyanobacterial harmful algal blooms (HAB) can affect human and animal health and welfare by degrading the quality of drinking water supplies, thereby complicating treatment for potable water, and forcing activity restrictions at recreational waterbodies. It is estimated that lakes and reservoirs t…

The Need

Cyanobacterial harmful algal blooms (HAB) can affect human and animal health and welfare by degrading the quality of drinking water supplies, thereby complicating treatment for potable water, and forcing activity restrictions at recreational waterbodies. It is estimated that lakes and reservoirs that serve as sources of drinking water for 30–48 million Americans may be periodically contaminated by algal toxins. Beyond the human health impacts resulting from cyanotoxins in drinking water supplies, CyanoHABs can have a variety of direct deleterious effects on aquatic ecosystems. The blooms result in a loss of water clarity, which suppresses the growth of aquatic plants, negatively affecting invertebrate and fish habitats.

The Technology

Cyanophage, viruses specific for cyanobacteria, are known for influencing on bloom formation and duration in various ways, including regulating the growth of cyanobacteria. Researchers at The Ohio State University led by Dr. Jiyoung Lee have isolated Cyanophage (Cyanophage Ma-LEP) from Western Lake Erie and were able to show that Cyanophage Ma-LEP can completely rupture the Cyanobacteria in combination with UV light treatment. With proper optimization and field application, Cyanophage Ma-LEP and UV can be a sustainable, economic, and environmentally friendly way of managing toxic cyanobacteria blooms.

Commercial Applications

  • Pharmaceutical research
  • Biotechnology industry

Benefits/ Advantages

  • Prevent water contamination and maintain aquatic ecosystems by regulating the growth of cyanobacteria
  • Provide a sustainable, economic, and environmentally friendly way of managing toxic cyanobacteria blooms